C. Fotsch: шукати на сайті Z-Library

Рік:

2005

Мова:

english

Файл:

PDF, 171 KB

english, 2005

A new class of bradykinin 1 receptor antagonists containing the piperidine acetic acid tetralin core

Christopher Fotsch, Gloria Biddlecome, Kaustav Biswas, Jian Jeff Chen, Derin C. D’Amico, Robert D. Groneberg, Nianhe Bruce Han, Feng-Yin Hsieh, Augustus Kamassah, Gondi Kumar, Dianna Lester-Zeiner, Qi

Журнал:

Рік:

2006

Мова:

english

Файл:

PDF, 138 KB

english, 2006

Structure−Activity Relationships of a Series of Pyrrolo[3,2-d]pyrimidine Derivatives and Related Compounds as Neuropeptide Y5 Receptor Antagonists

Norman, Mark H., Chen, Ning, Chen, Zhidong, Fotsch, Christopher, Hale, Clarence, Han, Nianhe, Hurt, Ray, Jenkins, Tracy, Kincaid, John, Liu, Longbin

Журнал:

Ophthalmology Clinics of North America

Рік:

2000

Мова:

english

Файл:

PDF, 302 KB

english, 2000

[IEEE 17th International Conference on Database and Expert Systems Applications (DEXA'06) - Krakow, Poland (04-08 Sept. 2006)] 17th International Conference on Database and Expert Systems Applications (DEXA'06) - XTC -- The XML Transformation Coordinator for XML Document Transformation Technologies

Fotsch, D., Speck, A.

Рік:

2006

Мова:

english

Файл:

PDF, 358 KB

english, 2006

[IEEE 18th International Conference on Database and Expert Systems Applications (DEXA 2007) - Regensburg, Germany (2007.09.3-2007.09.7)] 18th International Conference on Database and Expert Systems Applications (DEXA 2007) - A Generic Framework for Target-Specific Transformation Operators in XML Transformation Languages

Fotsch, Daniel

Рік:

2007

Мова:

english

Файл:

PDF, 313 KB

english, 2007

THE EFFECT OF THE WORLD- WIDE WEB ON YOU AND YOUR PATIENTS

FOTSCH, E

Журнал:

Рік:

2000

Мова:

english

Файл:

PDF, 612 KB

english, 2000

Multimode Resistance Training to Improve Baseball Batting Power

Ebben, William P., Fotsch, Alison, Hartz, Kristopher K.

Журнал:

Strength and Conditioning

Рік:

2006

Мова:

english

Файл:

PDF, 81 KB

english, 2006

The Building of a Superhighway Future at the New York World's Fair

Fotsch, Paul Mason

Журнал:

Cultural Critique

Рік:

2001

Мова:

english

Файл:

PDF, 2.35 MB

english, 2001

SAE Technical Paper Series [SAE International Earthmoving Industry Conference & Exposition - (AUG. 08, 1994)] SAE Technical Paper Series - Flexible Body Dynamic Simulation of a Large Mining Truck

Lohmann, Walter E., Fotsch, Paul D.

Рік:

1994

Мова:

english

Файл:

PDF, 686 KB

english, 1994

ChemInform Abstract: A Short, Facile Synthesis of 5-Substituted 3-Amino-1H-pyrrole-2-carboxylates.

Ning Chen, Yuelie Lu, Kumar Gadamasetti, Clarence R. Hurt, Mark H. Norman, Christopher Fotsch

Журнал:

Christopher Fotsch, et al. et al.

Рік:

2000

Файл:

PDF, 29 KB

2000

Design of a New Peptidomimetic Agonist for the Melanocortin Receptors Based on the Solution Structure of the Peptide Ligand, Ac-Nle-cyclo[Asp-Pro-DPhe-Arg-Trp-Lys]-NH2.

Журнал:

Рік:

2003

Мова:

english

Файл:

PDF, 63 KB

english, 2003

Synthesis of Novel Melanocortin 4 Receptor Agonists and Antagonists Containing a Succinamide Core.

Ning Xi, Clarence Hale, Michael G. Kelly, Mark H. Norman, Markian Stec, Shimin Xu, James W. Baumgartner, Christopher Fotsch

Журнал:

Christopher Fotsch, et al. et al.

Рік:

2004

Файл:

PDF, 180 KB

2004

Melanocortin Subtype-4 Receptor Agonists Containing a Piperazine Core with Substituted Aryl Sulfonamides.

Журнал:

Journal of Manufacturing Systems

Рік:

2005

Файл:

PDF, 14 KB

2005

Machine tool justification policies: Their effect on productivity and profitability

Richard J. Fotsch

Журнал:

Рік:

1984

Мова:

english

Файл:

PDF, 1.55 MB

english, 1984

Synthesis of novel melanocortin 4 receptor agonists and antagonists containing a succinamide core

Ning Xi, Clarence Hale, Michael G. Kelly, Mark H. Norman, Markian Stec, Shimin Xu, James W. Baumgartner, Christopher Fotsch

Журнал:

Katarina Flyrén, Lars O. Bergquist, Victor M. Castro, Christopher Fotsch, Lars Johansson, David J. St. Jean Jr., Lori Sutin, Meredith Williams

Рік:

2004

Мова:

english

Файл:

PDF, 199 KB

english, 2004

Piperidine amides as 11β-hydroxysteroid dehydrogenase type 1 inhibitors

Журнал:

Рік:

2007

Мова:

english

Файл:

PDF, 166 KB

english, 2007

Aryl sulfonamides containing tetralin allylic amines as potent and selective bradykinin B1 receptor antagonists

Qingyian Liu, Wenyuan Qian, Aiwen Li, Kaustav Biswas, Jian Jeffrey Chen, Christopher Fotsch, Nianhe Han, Chester Yuan, Leyla Arik, Gloria Biddlecome, Eileen Johnson, Gondi Kumar, Dianna Lester-Zeiner,

Журнал:

Рік:

2010

Мова:

english

Файл:

PDF, 1.08 MB

english, 2010

3-Oxo-2-piperazinyl acetamides as potent bradykinin B1 receptor antagonists for the treatment of pain and inflammation

Jian Jeffrey Chen, Thomas Nguyen, Derin C. D’Amico, Wenyuan Qian, Jason Human, Toshihiro Aya, Kaustav Biswas, Christopher Fotsch, Nianhe Han, Qingyian Liu, Nobuko Nishimura, Tanya A.N. Peterkin, Kevin

Журнал:

Minghan Wang, Christopher Fotsch

Рік:

2011

Мова:

english

Файл:

PDF, 836 KB

english, 2011

Small-Molecule Compounds that Modulate Lipolysis in Adipose Tissue: Targeting Strategies and Molecular Classes

Журнал:

Chemistry & Biology

Рік:

2006

Мова:

english

Файл:

PDF, 231 KB

english, 2006

Synthesis of a guanidino-sugar as a glycosyl cation mimic

Christopher H. Fotsch, Chi-Huey Wong

Журнал:

Tetrahedron Letters

Рік:

1994

Мова:

english

Файл:

PDF, 334 KB

english, 1994

Design of a new peptidomimetic agonist for the melanocortin receptors based on the solution structure of the peptide ligand, Ac-Nle-cyclo[Asp-Pro-dPhe-Arg-Trp-Lys]-NH2

Christopher Fotsch, Duncan M Smith, Jeffrey A Adams, Janet Cheetham, Michael Croghan, Elizabeth M Doherty, Clarence Hale, Mark A Jarosinski, Michael G Kelly, Mark H Norman, Nuria A Tamayo, Ning Xi, Ja

Журнал:

Рік:

2003

Мова:

english

Файл:

PDF, 201 KB

english, 2003

On-resin macrocyclization of peptides via intramolecular SnAr reactions

Christopher Fotsch, G. Kumaravel, Sushil K. Sharma, Arthur D. Wu, John S. Gounarides, N.R. Nirmala, Russell C. Petter

Журнал:

Chemical Biology & Drug Design

Рік:

1999

Мова:

english

Файл:

PDF, 327 KB

english, 1999

Solid-phase total synthesis of polymyxin B1

S.K. Sharma, A.D. Wu, N. Chandramouli, C. Fotsch, G. Kardash, K.W. Bair

Журнал:

Рік:

1999

Мова:

english

Файл:

PDF, 225 KB

english, 1999

Postoperative Schmerztherapie nach Tonsillektomie im Kindesalter

T. Fösel, S. Fötsch, O. Ebeling

Журнал:

HNO

Рік:

2005

Мова:

german

Файл:

PDF, 655 KB

german, 2005

Melanocortin subtype-4 receptor agonists containing a piperazine core with substituted aryl sulfonamides

Christopher Fotsch, Nianhe Han, Premilla Arasasingham, Yunxin Bo, Michelle Carmouche, Ning Chen, James Davis, Martin H. Goldberg, Clarence Hale, Feng-Yin Hsieh, Michael G. Kelly, Qingyian Liu, Mark H.

Журнал:

Diabetes, Obesity and Metabolism

Рік:

2005

Мова:

english

Файл:

PDF, 163 KB

english, 2005

Time of the day for 11β-HSD1 inhibition plays a role in improving glucose homeostasis in DIO mice

M. M. Véniant, C. Hale, R. Komorowski, M. M. Chen, D. J. St Jean, C. Fotsch, M. Wang

Журнал:

Рік:

2009

Мова:

english

Файл:

PDF, 146 KB

english, 2009

Structural Characterization and Pharmacodynamic Effects of an Orally Active 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor

Clarence Hale, Murielle Véniant, Zhulun Wang, Michelle Chen, Jocelyn McCormick, Rod Cupples, Dean Hickman, Xiaoshan Min, Athena Sudom, Haoda Xu, Guy Matsumoto, Christopher Fotsch, David J. St. Jean Jr

Журнал:

Chemical Biology & Drug Design

Рік:

2008

Мова:

english

Файл:

PDF, 419 KB

english, 2008

Mitigating Heterocycle Metabolism in Drug Discovery

St. Jean, David J., Fotsch, Christopher

Журнал:

Рік:

2012

Мова:

english

Файл:

PDF, 6.67 MB

english, 2012

Further Studies with the 2-Amino-1,3-thiazol-4(5H)-one Class of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors: Reducing Pregnane X Receptor Activity and Exploring Activity in a Monkey Pharmacodynamic Model

Fotsch, Christopher, Bartberger, Michael D., Bercot, Eric A., Chen, Michelle, Cupples, Rod, Emery, Maury, Fretland, Jenne, Guram, Anil, Hale, Clarence, Han, Nianhe

Журнал:

Journal of Organic Chemistry

Рік:

2008

Мова:

english

Файл:

PDF, 441 KB

english, 2008

A Short, Facile Synthesis of 5-Substituted 3-Amino-1H-pyrrole-2-carboxylates

Chen, Ning, Lu, Yuelie, Gadamasetti, Kumar, Hurt, Clarence R., Norman, Mark H., Fotsch, Christopher

Журнал:

Рік:

2000

Мова:

english

Файл:

PDF, 79 KB

english, 2000

Cytochrome P450-Mediated Epoxidation of 2-Aminothiazole-Based AKT Inhibitors: Identification of Novel GSH Adducts and Reduction of Metabolic Activation through Structural Changes Guided by in Silico and in Vitro Screening

Subramanian, Raju, Lee, Matthew R., Allen, John G., Bourbeau, Matthew P., Fotsch, Christopher, Hong, Fang-Tsao, Tadesse, Seifu, Yao, Guomin, Yuan, Chester C., Surapaneni, Sekhar

Журнал:

Chemical Research in Toxicology

Рік:

2010

Мова:

english

Файл:

PDF, 1.56 MB

english, 2010

Identification of a Nonpeptidic and Conformationally Restricted Bradykinin B1 Receptor Antagonist with Anti-Inflammatory Activity

D'Amico, Derin C., Aya, Toshi, Human, Jason, Fotsch, Christopher, Chen, Jian Jeffrey, Biswas, Kaustav, Riahi, Bobby, Norman, Mark H., Willoughby, Christopher A., Hungate, Randall

Журнал:

Рік:

2007

Мова:

english

Файл:

PDF, 84 KB

english, 2007

Design and synthesis of novel amide AKT1 inhibitors with selectivity over CDK2

Kate S. Ashton, David J. St. Jean Jr., Steve F. Poon, Matthew R. Lee, John G. Allen, Shiwen Zhang, Julie A. Lofgren, Xiaoling Zhang, Christopher Fotsch, Randall Hungate

Журнал:

Chou, Wen-Chih, Fotsch, Christopher, Wong, Chi-Huey

Рік:

2011

Мова:

english

Файл:

PDF, 1.83 MB

english, 2011

Synthesis of Nitrocyclitols Based on Enzymic Aldol Reaction and Intramolecular Nitroaldol Reaction

Журнал:

Journal of Organic Chemistry

Рік:

1995

Мова:

english

Файл:

PDF, 264 KB

english, 1995

Novel Vanilloid Receptor-1 Antagonists: 1. Conformationally Restricted Analogues of trans -Cinnamides †

Norman, Mark H., Zhu, Jiawang, Fotsch, Christopher, Bo, Yunxin, Chen, Ning, Chakrabarti, Partha, Doherty, Elizabeth M., Gavva, Narender R., Nishimura, Nobuko, Nixey, Thomas, Ognyanov, Vassil I., Rzasa

Журнал:

Рік:

2007

Мова:

english

Файл:

PDF, 484 KB

english, 2007

Discovery of Potent, Orally Available Vanilloid Receptor-1 Antagonists. Structure−Activity Relationship of N -Aryl Cinnamides

Doherty, Elizabeth M., Fotsch, Christopher, Bo, Yunxin, Chakrabarti, Partha P., Chen, Ning, Gavva, Narender, Han, Nianhe, Kelly, Michael G., Kincaid, John, Klionsky, Lana, Liu, Qingyian, Ognyanov, Vas

Журнал:

Рік:

2005

Мова:

english

Файл:

PDF, 321 KB

english, 2005

Novel Vanilloid Receptor-1 Antagonists: 2. Structure−Activity Relationships of 4-Oxopyrimidines Leading to the Selection of a Clinical Candidate

Doherty, Elizabeth M., Fotsch, Christopher, Bannon, Anthony W., Bo, Yunxin, Chen, Ning, Dominguez, Celia, Falsey, James, Gavva, Narender R., Katon, Jodie, Nixey, Thomas, Ognyanov, Vassil I., Pettus, L

Журнал:

Fotsch, Christopher, Wang, Minghan

Рік:

2007

Мова:

english

Файл:

PDF, 280 KB

english, 2007

Blockade of Glucocorticoid Excess at the Tissue Level: Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1 as a Therapy for Type 2 Diabetes

Журнал:

Рік:

2008

Мова:

english

Файл:

PDF, 136 KB

english, 2008

2-Amino-1,3-thiazol-4(5 H )-ones as Potent and Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors: Enzyme−Ligand Co-Crystal Structure and Demonstration of Pharmacodynamic Effects in C57Bl/6 Mice

Johansson, Lars, Fotsch, Christopher, Bartberger, Michael D., Castro, Victor M., Chen, Michelle, Emery, Maurice, Gustafsson, Sonja, Hale, Clarence, Hickman, Dean, Homan, Evert, Jordan, Steven R., Komo

Журнал:

Fotsch, Christopher H., Chamberlin, A. Richard

Рік:

2008

Мова:

english

Файл:

PDF, 276 KB

english, 2008

Stereochemical control in reactions of nucleophiles with oxocarbenium ions formed by intramolecular opening of activated epoxides by neighboring carbonyl groups

Журнал:

Journal of Organic Chemistry

Рік:

1991

Мова:

english

Файл:

PDF, 1.01 MB

english, 1991

Discovery and Optimization of Substituted 1-(1-Phenyl-1 H -pyrazol-3-yl)methanamines as Potent and Efficacious Type II Calcimimetics

Poon, Steve F., St. Jean, David J., Harrington, Paul E., Henley, Charles, Davis, James, Morony, Sean, Lott, Fred D., Reagan, Jeff D., Lu, Jenny Ying-Lin, Yang, Yuhua, Fotsch, Christopher

Журнал:

Fotsch, Christopher, Sonnenberg, Jennifer D., Chen, Ning, Hale, Clarence, Karbon, William, Norman, Mark H.

Рік:

2009

Мова:

english

Файл:

PDF, 885 KB

english, 2009

Synthesis and Structure−Activity Relationships of Trisubstituted Phenyl Urea Derivatives as Neuropeptide Y5 Receptor Antagonists

Журнал:

Allen, John G., Fotsch, Christopher, Babij, Philip

Рік:

2001

Мова:

english

Файл:

PDF, 174 KB

english, 2001

Emerging Targets in Osteoporosis Disease Modification

Журнал:

Рік:

2010

Мова:

english

Файл:

PDF, 2.09 MB

english, 2010

Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1 H -benzimidazoles

Ognyanov, Vassil I., Balan, Chenera, Bannon, Anthony W., Bo, Yunxin, Dominguez, Celia, Fotsch, Christopher, Gore, Vijay K., Klionsky, Lana, Ma, Vu V., Qian, Yi-Xin, Tamir, Rami, Wang, Xianghong, Xi, N

Журнал:

Рік:

2006

Мова:

english

Файл:

PDF, 739 KB

english, 2006

Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept

Ashton, Kate S., Andrews, Kristin L., Bryan, Marion C., Chen, Jie, Chen, Kui, Chen, Michelle, Chmait, Samer, Croghan, Michael, Cupples, Rod, Fotsch, Christopher, Helmering, Joan, Jordan, Steve R., Kur

Журнал:

Рік:

2014

Мова:

english

Файл:

PDF, 4.18 MB

english, 2014

Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 3. Structure–Activity Relationships within the Aryl Carbinol Region of the N -Arylsulfonamido- N ′-arylpiperazine Series

Nishimura, Nobuko, Norman, Mark H., Liu, Longbin, Yang, Kevin C., Ashton, Kate S., Bartberger, Michael D., Chmait, Samer, Chen, Jie, Cupples, Rod, Fotsch, Christopher, Helmering, Joan, Jordan, Steven

Журнал:

Рік:

2014

Мова:

english

Файл:

PDF, 884 KB

english, 2014

Metabolism-guided discovery of a potent and orally bioavailable urea-based calcimimetic for the treatment of secondary hyperparathyroidism

Wehn, Paul M., Harrington, Paul E., Carlson, Timothy J., Davis, James, Deprez, Pierre, Fotsch, Christopher H., Grillo, Mark P., Lu, Jenny Ying-Lin, Morony, Sean, Pattabiraman, Kanaka, Poon, Steve F.,

Журнал:

Harrington, Paul E., Bourbeau, Matthew P., Fotsch, Christopher, Frohn, Michael, Pickrell, Alexander J., Reichelt, Andreas, Sham, Kelvin, Siegmund, Aaron C., Bailis, Julie M., Bush, Tammy, Escobar, Son

Рік:

2013

Мова:

english

Файл:

PDF, 1.14 MB

english, 2013

The optimization of aminooxadiazoles as orally active inhibitors of Cdc7

Журнал: